Leaf & Comb Review

LipoTrine Review: What's in the Berberine Gummy and Is It Worth the Price?

Updated 2026-10-08 · Leaf & Comb Review Editorial Team

Disclosure: some links on this page are affiliate links. If you buy through them we may earn a commission, at no extra cost to you. This content is for information only and is not medical advice — talk to your doctor before starting any supplement.

Short answer: LipoTrine is a low-calorie gummy with 40 mg berberine, 28 mg cinnamon extract and 25 mcg chromium. The label is unusually clear, but the berberine dose is far below amounts used in most studies.

What is LipoTrine?

LipoTrine is a daily gummy sold from its own website through BuyGoods and shipped, according to the page, from Aurora, Colorado. It is marketed to adults over 45 for weight management, metabolism, energy and support for blood sugar that is already in the normal range. Each bottle holds 30 gummies.

Unlike most products in this niche, the LipoTrine sales page is a readable text page rather than a video-only presentation, and it shows a supplement facts panel with real numbers.

LipoTrine supplement facts, per the official website

Per gummy Amount
Berberine HCl 40 mg
Cinnamon bark extract 28 mg
Chromium (as chromium picolinate) 25 mcg (71% of the Daily Value)
Carbohydrate 1 g
Calories 0

Other ingredients listed: maltitol, xylitol, water, pectin, rice flour, citric acid, acesulfame K, stevia leaf extract, sodium citrate, natural flavor and FD&C Red 40.

Two details to notice. First, the sweeteners are sugar alcohols (maltitol and xylitol), which can cause gas or loose stools in some people. Second, xylitol is highly toxic to dogs, so keep the bottle out of reach of pets.

What research says about LipoTrine's three active ingredients

Berberine. According to NCCIH's goldenseal fact sheet, berberine has been studied for effects on blood sugar, cholesterol and body weight, though little is absorbed orally. Published trials have generally used several hundred milligrams per day, split into doses. At 40 mg per gummy, LipoTrine supplies a small fraction of that. See our berberine guide for context.

Cinnamon. NCCIH's cinnamon page says research does not clearly show that cinnamon supplements help control blood sugar, partly because studies used different types and amounts.

Chromium. The NIH Office of Dietary Supplements' chromium fact sheet reports only a very small weight benefit from chromium supplements, unlikely to matter for health or appearance. It also warns that chromium may cause low blood sugar when combined with insulin or metformin and may reduce absorption of levothyroxine.

Check LipoTrine's official price

LipoTrine price and guarantee (verified October 2026)

Package Per bottle Total Shipping
2 bottles $79 $158 Not stated
3 bottles $69 $207 Free (US)
6 bottles $49 $294 Free (US)

The page says there is no subscription and no automatic rebilling. The guarantee is 60 days from purchase, requested by email, and the FAQ states that bottles do not need to be sent back. That is friendlier than the return-everything policies of several competitors.

The package labels on the page are confusing: the 2-bottle option is labeled a "30-day supply" even though each bottle holds 30 gummies. Also, the FAQ mentions taking "two capsules," which does not match a gummy product. Follow the directions on the bottle you receive.

LipoTrine's dose next to research doses

Ingredient LipoTrine per gummy What research or references commonly discuss
Berberine HCl 40 mg Many human trials used around 500 mg, two or three times a day
Cinnamon bark extract 28 mg Studies used varied types and amounts; NCCIH says results are unclear
Chromium 25 mcg NIH ODS notes only a very small weight effect from supplements

Seen this way, LipoTrine reads as a low-dose, gentle product rather than a research-dose berberine supplement. That may be a plus for people who are cautious about side effects, and a minus for people expecting the effects described in berberine studies.

Using LipoTrine sensibly

If your doctor agrees you can try it, take it with a meal, since berberine commonly causes stomach upset on an empty stomach. Do not combine it with another berberine product such as Valiora or Honey Burn. Keep notes on how your stomach handles the sugar alcohols during the first days, and set a calendar reminder a week before the 60-day refund window closes so you can decide calmly.

Who LipoTrine may suit

Who should avoid LipoTrine or ask a doctor first

Honest cons of LipoTrine

How LipoTrine compares

The closest alternative is Valiora, a capsule that combines berberine with green tea and apple cider vinegar but does not list amounts. We compare them in Valiora vs LipoTrine. If you are weighing a gummy against a honey blend, read Honey Burn vs LipoTrine.

See LipoTrine packages

Sources consulted: nccih.nih.gov, ods.od.nih.gov.

Frequently asked questions

How much berberine is in LipoTrine?

The official supplement facts list 40 mg of berberine HCl per gummy, along with 28 mg cinnamon bark extract and 25 mcg chromium.

Is LipoTrine a subscription?

No. The official page says it is a one-time purchase with no automatic billing.

Do I have to return the bottles for a LipoTrine refund?

According to the official FAQ, no. You email the company within 60 days of purchase to request the refund.

Is LipoTrine safe for pets in the house?

LipoTrine contains xylitol, which is dangerous for dogs. Store the bottle where pets cannot reach it.